The elegant Lucerne is Buick's flagship sedan, boasting a plush interior and smooth road manners. It provides comfortable seating for up to six passengers, along with premium amenities and comprehensive safety equipment.

The front-wheel drive Lucerne is offered in four trim levels: CX, CXL, CXL Premium and Super. The CX and CXL variants are equipped with a 227-hp 3.9-liter V6 engine, while the Super gets a more powerful 292-hp 4.6-liter Northstar V8; both engines are mated to a four-speed automatic transmission. The CX is outfitted with 17-inch alloy wheels, air conditioning and satellite radio; CXL trims add dual-zone automatic climate control, leather upholstery, heated front seats, Bluetooth wireless connectivity and a heated steering wheel. The CXL Premium and Super trims are further equipped with chrome wheels (18-inch on Super) and a 6-disc CD changer, while the Super also boasts an adaptive sport-tuned suspension with Magnetic Ride Control, power sunroof, ventilated front seats and suede/leather upholstery. Safety features found on every Lucerne include traction control, 4-wheel anti-lock disc brakes, front side-impact airbags, overhead curtain airbags for front and rear passengers, a tire pressure monitoring system and OnStar service. Additional safety enhancements, including Stabilitrak electronic stability control and Ultrasonic rear parking assist, as well as Lane Departure Warning and Side Blind Zone Alert systems, are standard on CXL Premium and Super trims.

For 2010, the Buick Lucerne carries over with minimal adjustments to standard and optional equipment. All trims now get standard front fog lamps, and the Super exterior appearance is expanded across the full lineup, including a front color-keyed fascia with integrated chrome grille and body-color rocker panel moldings.